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Rabbit Anti-MEST  antibody (bs-18797R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-18797R
英文名称 MEST
中文名称 中胚层特异性转录同源蛋白MEST抗体
别    名 DKFZp686L18234; EC 3.-.-.-; Mesoderm specific transcript (mouse) homolog; Mesoderm specific transcript homolog (mouse); Mesoderm-specific transcript homolog protein; MEST; MEST_HUMAN; MGC111102; MGC8703; OTTHUMP00000210362; OTTHUMP00000210364; OTTHUMP00000210367; Paternally expressed gene 1; Paternally-expressed gene 1 protein; PEG1.  
研究领域 细胞生物  免疫学  转录调节因子  淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 39kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MEST: 101-200/335 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in hydatidiform moles, but barely expressed in dermoid cysts. Biallelic expression is detected in blood lymphocytes. Seems to imprinted in an isoform-specific manner rather than in a tissue-specific manner in lymphocytes. Isoform 1 is expressed only from the paternal allele. Isoform 2 is expressed from both the paternal allele and the maternal allele.

Similarity:
Belongs to the AB hydrolase superfamily.

SWISS:
Q5EB52

Gene ID:
4232

Database links:

Entrez Gene: 4232 Human

Entrez Gene: 404180 Cow

Entrez Gene: 607717 Dog

Entrez Gene: 17294 Mouse

Entrez Gene: 100147710 Pig

Entrez Gene: 58827 Rat

Omim: 601029 Human

SwissProt: Q2HJM9 Cow

SwissProt: Q5EB52 Human

SwissProt: Q07646 Mouse

SwissProt: Q6P5P5 Rat

Unigene: 270978 Human

Unigene: 59431 Rat



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