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MARS2 Rabbit pAb (bs-18683R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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产品编号 bs-18683R
英文名称 MARS2 Rabbit pAb
中文名称 甲硫氨酸转运RNA合成酶2抗体
别    名 mars2; Methionine tRNA ligase 2; Methionine tRNA ligase 2 mitochondrial; Methionine tRNA ligase; Methionine tRNA synthetase 2; Methionine--tRNA ligase; Methionyl tRNA synthetase 2 mitochondrial; Methionyl tRNA synthetase mitochondrial; Methionyl-tRNA synt  
研究领域 细胞生物  神经生物学  信号转导  转运蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat (predicted: Human,Mouse,Cow,Dog,Horse)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 63 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MARS2: 31-130/593 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). [provided by RefSeq, Apr 2014]

DISEASE:
Spastic ataxia 3, autosomal recessive (SPAX3) [MIM:611390]: A neurologic disorder characterized by cerebellar ataxia, ataxic gait, spasticity, and hyperreflexia. Other variable features include dysarthria, dysmetria, mild cognitive impairment, urinary urgency and dystonic positioning. Note: The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the class-I aminoacyl-tRNA synthetase family.

SWISS:
Q96GW9

Gene ID:
92935

Database links:

Entrez Gene: 92935 Human

Omim: 609728 Human

SwissProt: Q96GW9 Human

Unigene: 116602 Human

Unigene: 744330 Human



产品图片
Sample: Stomach (Rat) Lysate at 40 ug Primary: Anti-MARS2 (bs-18683R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 63 kD Observed band size: 65 kD
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