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Rabbit Anti-LYPD3  antibody (bs-18572R)  
~~~促销代码KT202411~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-18572R
英文名称 Rabbit Anti-LYPD3  antibody
中文名称 LYPD3抗体
别    名 C4.4A; FLJ10525; GPI-anchored metastasis-associated protein C4.4A homolog; GPI-anchored metastasis-associated protein homolog; Ly6/PLAUR domain-containing protein 3; LYPD3_HUMAN; Matrigel-induced gene C4 protein; MIG-C4; SHINC3.  
研究领域 肿瘤  细胞类型标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Rabbit)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 33kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LYPD3: 201-300/346 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Predicted to enable laminin binding activity. Predicted to act upstream of or within cell-matrix adhesion. Located in extracellular space. [provided by Alliance of Genome Resources, Nov 2021]

Function:
Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.

Subunit:
Binds laminin-1 and laminin-5. Interacts with LGALS3 By similarity. Interacts with AGR2 and AGR3.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed in placenta, skin and urothelium. Found in suprabasal keratinocytes of chronic wounds. Weak expression is found in esophagus and peripheral blood mononuclear cells. Found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers.

Post-translational modifications:
N-glycosylated and O-glycosylated.

Similarity:
Contains 2 UPAR/Ly6 domains.

SWISS:
O95274

Gene ID:
27076

Database links:

Entrez Gene: 27076 Human

Omim: 609484 Human

SwissProt: O95274 Human

Unigene: 631594 Human



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