产品编号 | bs-18570R |
英文名称 | LYPD1 Rabbit pAb |
中文名称 | LYPD1蛋白抗体 |
别 名 | FLJ41033; LY6/PLAUR domain containing 1; Ly6/PLAUR domain-containing protein 1; Lypd1; LYPD1_HUMAN; LYPDC1; MGC29643; PHTS; Putative HeLa tumor suppressor. |
研究领域 | 细胞生物 细胞凋亡 表观遗传学 细胞膜蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human,Mouse,Rat,Rabbit) |
产品应用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 13 kDa |
检测分子量 | |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LYPD1: 51-141/141 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
LYPD1 is a 141 amino acid protein that contains one UPAR/Ly6 domain. LYPD1 is a cell membrane protein expressed as three isoforms and encoded by a gene mapping to human chromosome 2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes. Subcellular Location: Cell membrane. Similarity: Contains 1 UPAR/Ly6 domain. SWISS: Q8N2G4 Gene ID: 116372 Database links: Entrez Gene: 116372 Human Entrez Gene: 72585 Mouse Omim: 610450 Human SwissProt: Q8N2G4 Human SwissProt: Q8BLC3 Mouse Unigene: 432395 Human Unigene: 741324 Human Unigene: 490405 Mouse Unigene: 231867 Rat |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |