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Rabbit Anti-KIF15  antibody (bs-10693R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-10693R
英文名称 KIF15
中文名称 驱动蛋白家族成员15抗体
别    名 Kinesin like protein 7; KLP2; FLJ25667; HKLP2; Kinesin family member 15; Kinesin like protein 2; Kinesin like protein 7; Kinesin like protein KIF15; KLP2; KNSL7; Linesin like 7; NY BR 62; NYBR62; Serologically defined breast cancer antigen NY BR 62; Serologically defined breast cancer antigen NYBR62; FLJ25667; KIF15_HUMAN.  
研究领域 细胞生物  细胞骨架  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Horse)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 160kDa
细胞定位 细胞浆 细胞膜 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIF15: 101-200/1388 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 KIF15 belongs to the kinesin-like protein family and contains 1 kinesin-motor domain. KIF15 is the plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly.

Function:
Plus-end directed kinesin-like motor enzyme involved inmitotic spindle assembly.

Subunit:
Interacts with MKI67 and TPX2.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton, spindle.Note=Detected during the interphase in the cytoplasm as finelypunctuate pattern and irregularly shaped dots. Detected duringmitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis.Localizes at the central spindle at anaphase.Localizes at the sites of invaginating cell membranes, a positionthat corresponds to the location of the contractile actomyosin ringof dividing cells. Colocalizes with actin ininterphase. Colocalizes in dendrites and in growthcone of axons with microtubules.

Tissue Specificity:
Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis.

Similarity:
Belongs to the kinesin-like protein family. KLP2subfamily.
Contains 1 kinesin-motor domain.

SWISS:
Q9NS87

Gene ID:
56992

Database links:

Entrez Gene: 56992 Human

Entrez Gene: 209737 Mouse

Entrez Gene: 353302 Rat

SwissProt: Q9NS87 Human

SwissProt: Q6P9L6 Mouse

SwissProt: Q7TSP2 Rat

 



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