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LCLAT1 Rabbit pAb (bs-18190R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-18190R
英文名称 LCLAT1 Rabbit pAb
中文名称 心磷脂酰基转移酶1抗体
别    名 1AGPAT8; AGPAT8; ALCAT1; HSRG1849; LPLAT6; LYCAT; UNQ1849; 1-AGPAT 8; Gm91; AGPATP8; LCLT1_HUMAN; LCLAT1; 1-acylglycerol-3-phosphate O-acyltransferase 8 (1-AGP acyltransferase 8 | 1-AGPAT 8); Acyl-CoA:lysocardiolipin acyltransferase 1; 2.3.1.-; LCLT1_MOUS  
Specific References  (1)     |     bs-18190R has been referenced in 1 publications.
[IF=3.115] Huiyuan Gong. et al. Upregulation of LPGAT1 Enhances Lung Adenocarcinoma Proliferation. FRONT BIOSCI-LANDMRK. 2023 May;28(5):89  WB ;  Human.  
研究领域 细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse,Rat (predicted: Human,Rabbit,Sheep,Cow,Dog,Horse)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 49 kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LCLAT1: 261-360/414 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Expressed at higher level in heart, kidney and pancreas than in brain, spleen, liver, lung, small intestine and placenta.

Similarity:
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

SWISS:
Q6UWP7

Gene ID:
253558

Database links:

Entrez Gene: 253558 Human

Entrez Gene: 225010 Mouse

Entrez Gene: 100217396 Pig

Omim: 614241 Human

SwissProt: Q6UWP7 Human

SwissProt: Q3UN02 Mouse

Unigene: 468048 Human

Unigene: 662770 Human

Unigene: 329194 Mouse



产品图片
Sample: Liver(Mouse)Lysate at 40 ug Kidney (Mouse)Lysate at 40 ug Primary: Anti-LCLAT1(bs-18190R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 49kD Observed band size: 49kD
Sample:Heart (Mouse)Lysate at 40 ug Primary: Anti-LCLAT1(bs-18190R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 49kD Observed band size: 49kD
Sample: Heart (Mouse) Lysate at 40 ug Heart (Rat) Lysate at 40 ug Primary: Anti-LCLAT1 (bs-18190R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD
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