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Rabbit Anti-HVCN1  antibody (bs-18109R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-18109R
英文名称 HVCN1
中文名称 氢离子电压门控通道蛋白1抗体
别    名 HV 1; HV1; HVCN 1; HVCN1; HVCN1_HUMAN; Hydrogen voltage gated channel 1; Hydrogen voltage-gated channel 1; Voltage gated hydrogen channel 1; Voltage sensor domain only protein; Voltage sensor domain-only protein; Voltage-gated hydrogen channel 1; VSOP.  
研究领域 肿瘤  细胞生物  免疫学  信号转导  淋巴细胞  b-淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 32kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HVCN1: 201-273/273 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis.

Subcellular Location:
Membrane.

Tissue Specificity:
Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen.

Similarity:
Belongs to the hydrogen channel family.

SWISS:
Q96D96

Gene ID:
84329

Database links:

Entrez Gene: 84329 Human

Entrez Gene: 74096 Mouse

Omim: 611227 Human

SwissProt: Q96D96 Human

SwissProt: Q3U2S8 Mouse

Unigene: 211511 Human

Unigene: 334637 Human

Unigene: 28804 Mouse



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