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Rabbit Anti-HLRC1  antibody (bs-18046R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-18046R
英文名称 HLRC1
中文名称 脱氧双加氧酶抗体
别    名 Deoxyhypusine dioxygenase; Deoxyhypusine hydroxylase; Deoxyhypusine hydroxylase/monooxygenase; Deoxyhypusine monooxygenase; Dohh; DOHH_HUMAN; hDOHH; HEAT like PBS lyase repeat containing; HEAT like repeat containing protein 1; HEAT-like repeat-containing protein 1; MGC4293.  
研究领域 肿瘤  细胞生物  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 33kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HLRC1: 1-100/302 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a metalloenzyme that catalyzes the last step in the conversion of lysine to the unique amino acid hypusine in eukaryotic initiation factor 5A. The encoded protein hydroxylates deoxyhypusine to form hypusine in the mature eukaryotic initiation factor 5A protein. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009]

Function:
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

Similarity:
Belongs to the deoxyhypusine hydroxylase family.
Contains 5 HEAT-like PBS-type repeats.

SWISS:
Q9BU89

Gene ID:
83475

Database links:

Entrez Gene: 43740 Fruit fly (Drosophila melanogaster)

Entrez Gene: 83475 Human

Entrez Gene: 102115 Mouse

Entrez Gene: 314644 Rat

Entrez Gene: 321732 Zebrafish

Omim: 611262 Human

SwissProt: Q9V9U4 Fruit fly (Drosophila melanogaster)

SwissProt: Q9BU89 Human

SwissProt: Q99LN9 Mouse

SwissProt: Q5PPJ4 Rat

SwissProt: Q7ZUX6 Zebrafish

Unigene: 29814 Fruit fly (Drosophila melanogaster)

Unigene: 37858 Fruit fly (Drosophila melanogaster)

Unigene: 515064 Human

Unigene: 609012 Human

Unigene: 294975 Mouse

Unigene: 38296 Rat

Unigene: 2393 Zebrafish



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