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SPOCK3 Rabbit pAb (bs-17683R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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产品编号 bs-17683R
英文名称 SPOCK3 Rabbit pAb
中文名称 富含半胱氨酸酸性分泌/骨粘连蛋白多糖抗体
别    名 HSAJ1454; OTTHUMP00000219853; OTTHUMP00000219854; OTTHUMP00000219857; OTTHUMP00000219858; OTTHUMP00000219862; OTTHUMP00000219864; OTTHUMP00000219865; OTTHUMP00000219866; OTTHUMP00000219867; OTTHUMP00000219868; Sparc/osteonectin, cwcv and kazal like domains proteoglycan(testican) 3; SPARC/osteonectin, CWCV, and Kazal like domains proteoglycan 3; TES 3; testican 3; TICN3  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human (predicted: Mouse,Rat,Dog)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 49 kDa
检测分子量
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPOCK3: 181-280/436 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Function:
SPOCK3 may participate in diverse steps of neurogenesis. It inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP and may also interfere with tumor invasion.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Similarity:
Contains 1 Kazal-like domain. Contains 1 thyroglobulin type-1 domain.

SWISS:
Q9BQ16

Gene ID:
50859

Database links:

Entrez Gene: 50859 Human

Entrez Gene: 72902 Mouse

Entrez Gene: 306404 Rat

Omim: 607989 Human

SwissProt: Q9BQ16 Human

SwissProt: Q8BKV0 Mouse



产品图片
Sample: 293T Cell (Human) Lysate at 40 ug Primary: Anti-SPOCK3 (bs-17683R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 48 kD
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