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Rabbit Anti-SIDT1  antibody (bs-17484R)  
~~~促销代码KT202411~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-17484R
英文名称 Rabbit Anti-SIDT1  antibody
中文名称 SIDT1蛋白抗体
别    名 AW045928; B830021E24Rik; FLJ20174; Msid2; OTTMUSP00000032144; SID 1; SID1; SID-1; SID1 transmembrane family member 1; SID1 transmembrane family, member 1; SIDT1; SIDT1_HUMAN.  
研究领域 肿瘤  细胞生物  跨膜蛋白  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow)
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 92kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SIDT1: 61-160/827 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 SID-1 and SID-2 belong to the systemic RNA interference defective-1 (SID1) family of transmembrane proteins. SID-1, originally identified in C. elegans, is an 827 amino acid protein. It localizes to the cell membrane and contains eleven transmembrane domains. This suggests that SID-1 possibly functions as a channel protein. The overexpression of SID-1 enhances double stranded RNA (dsRNA) uptake in pancreatic ductal adenocarcinoma cells. SID-2, also first identified in C. elegans, is an 832 amino acid protein with multiple transmembrane domains. At least two isoforms exist for SID-2 due to alternative splicing. Isoform 2 contains an additional 21 amino acids after residue 387 and has an alternate sequence that is 8 amino acids shorter for residues 814 to 832 of isoform 1.

Subcellular Location:
Membrane.

Similarity:
Belongs to the SID1 family.

SWISS:
Q9NXL6

Gene ID:
54847

Database links:

Entrez Gene: 54847 Human

Entrez Gene: 320007 Mouse

Entrez Gene: 288109 Rat

Omim: 606816 Human

SwissProt: Q9NXL6 Human

SwissProt: Q6AXF6 Mouse

SwissProt: Q6Q3F5 Rat

Unigene: 591291 Human

Unigene: 242144 Mouse

Unigene: 51246 Rat



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