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Rabbit Anti-HS3ST3B1  antibody (bs-17391R)  
~~~促销代码KT202411~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-17391R
英文名称 Rabbit Anti-HS3ST3B1  antibody
中文名称 HS3ST3B1蛋白抗体
别    名 3-OST-3B; h3-OST-3B; Heparan sulfate 3-O-sulfotransferase 3B1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1; Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; HS3SB_HUMAN; HS3ST3B1.  
研究领域 细胞生物  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 43kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HS3ST3B1: 201-300/390 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta. [provided by RefSeq, Jul 2008]

Function:
Transfers a sulfuryl group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.

Subcellular Location:
Golgi apparatus membrane.

Tissue Specificity:
Ubiquitous. Most abundant in liver and placenta, followed by heart and kidney.

Similarity:
Belongs to the sulfotransferase 1 family.

SWISS:
Q9Y662

Gene ID:
9953

Database links:

Entrez Gene: 9953 Human

SwissProt: Q9Y662 Human

Unigene: 48384 Human



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