| 产品编号 | bs-17247R |
| 英文名称 | SBEM |
| 中文名称 | 粘蛋白样蛋白1抗体 |
| 别 名 | mucin like 1; mucin-like 1; Mucin-like protein 1; MUCL1; MUCL1_HUMAN; Protein BS106; Small breast epithelial mucin. |
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Specific References (1) | bs-17247R has been referenced in 1 publications.
[IF=8.408] Hu Xi′e. et al. Clinical and biological heterogeneities in triple-negative breast cancer reveals a non-negligible role of HER2-low. BREAST CANCER RES. 2023 Dec;25(1):1-22 IF ; Human.
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| 研究领域 | 肿瘤 细胞生物 信号转导 细胞粘附分子 细胞类型标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 7kDa |
| 细胞定位 | 细胞膜 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SBEM: 51-90/90 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
SBEM is a 90 amino acid secreted membrane protein that may play a role as marker for the diagnosis of metastatic breast cancer. SBEM contains three tandem copies of a neutral octapeptide core repeat, and its N- and C-terminal regions are charged and fairly polar. These features are similar to many sialomucins, although the SBEM protein lacks a transmembrane domain and is shorter than most other known epithelial mucins. Expressed in mammary, salivary glands, prostate and also in lung, SBEM is mainly expressed in cancer cell lines of breast origin. SBEM is also highly expressed in lymph node-positive compared with node-negative tumors and in all lymph node containing metastatic cells. The SBEM gene is conserved in chimpanzee, cow, mouse, rat, chicken, zebrafish, C.elegans and M.grisea, and maps to human chromosome 12q13.2. Function: May play a role as marker for the diagnosis of metastatic breast cancer. Subcellular Location: O-glycosylated. Tissue Specificity: Expressed in mammary, salivary glands and prostate. Also detected in lung. Mainly expressed in cancer cell lines of breast origin. Highly expressed in lymph node-positive compared with node-negative tumors. Detected in all lymph node containing metastatic cells. Post-translational modifications: O-glycosylated. SWISS: Q96DR8 Gene ID: 11843 Database links: Entrez Gene: 118430 Human Omim: 610857 Human SwissProt: Q96DR8 Human Unigene: 348419 Human |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
