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Rabbit Anti-TOM1  antibody (bs-17222R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-17222R
英文名称 TOM1
中文名称 TOM1蛋白抗体
别    名 FLJ33404; OTTHUMP00000028777; Target of myb 1; TOM1_HUMAN; Target of Myb protein 1; Target of myb1; TOM 1.  
研究领域 细胞生物  转录调节因子  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,Chimpanzee,Rhesus monkey)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 54kDa
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TOM1: 1-100/492 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Function:
TOM1 may be involved in intracellular trafficking. In conjunction with Tollip it plays an important role in recruiting clathrin onto endosomes and may modulate endosomal functions.

Subunit:
Interacts with ZFYVE16; interaction is required to target it to endosomes.

Subcellular Location:
Cytoplasm. Membrane; Peripheral membrane protein

Tissue Specificity:
Widely expressed. Highly expressed in skeletal muscle, heart, placenta and liver

Similarity:
Belongs to the TOM1 family.
Contains 1 GAT domain.
Contains 1 VHS domain.

SWISS:
O60784

Gene ID:
10043

Database links:

Entrez Gene: 10043 Human

Entrez Gene: 608746 Dog

Entrez Gene: 21968 Mouse

Entrez Gene: 361370 Rat

Entrez Gene: 717499 Rhesus monkey

Omim: 604700 Human

SwissProt: O60784 Human

SwissProt: O88746 Mouse

SwissProt: Q5XI21 Rat



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