| 产品编号 | bs-17165R |
| 英文名称 | TPGS1 |
| 中文名称 | 电压门控离子通道蛋白TPGS1抗体 |
| 别 名 | C19orf20; two pore segment channel 1; Gene trap ROSA b geo 22; GTRGEO22; PGs1; Tubulin polyglutamylase complex subunit 1. |
| 研究领域 | 细胞生物 信号转导 通道蛋白 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Dog,Cow,Rabbit,Sheep) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 31kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TPGS1: 21-120/290 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
TPCN1 is a widely expressed, 816 amino acid voltage-gated cation channel protein with predominant expression in lung, liver, heart and kidney. In the kidney, TPCN1 localizes to the inner medullary collecting ducts. In contrast with the distantly related four-domain voltage-gated calcium and sodium channels and the more closely related four-domain ion transport protein located on the surface of sperm cells (CatSper), TPCN1 is a two-domain channel. Similar to the four-domain channel structure, each of the two homologous domains that comprise TPCN1 contains six transmembrane segments (S1-S6) with a pore loop between S5 and S6 and a voltage sensor segment that is positively charged. TPCN1 has hydrophilic N- and C-termini that localize to the cytoplasm. Function: TPGS1 may act in the targeting of the tubulin polyglutamylase complex. It is required for the development of the spermatid flagellum. Subunit: Part of the neuronal tubulin polyglutamylase complex which contains TPGS1, TPGS2, TTLL1, LRRC49 and NICN1. Subcellular Location: Microtubule. SWISS: Q6ZTW0 Gene ID: 91978 Database links: Entrez Gene: 91978 Human Entrez Gene: 110012 Mouse SwissProt: Q6ZTW0 Human SwissProt: Q99MS8 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
