| 产品编号 | bs-17068R |
| 英文名称 | Kir2.2 |
| 中文名称 | 钾离子通道Kir2.2抗体 |
| 别 名 | ATP sensitive inward rectifier potassium channel 12; ATP-sensitive inward rectifier potassium channel 12; hIRK; Human high conductance inward rectifier potassium channel alpha; Inward rectifier K; Inward rectifier K(+) channel Kir2.2; Inward rectifier K(+) channel Kir2.2v; inwardly rectifying subfamily J member 12; IRK-2; IRK12_HUMAN; IRK2; KCNJ12; kcnj12x; KCNJN1; Kir2.2v; Potassium channel; Potassium channel inwardly rectifying subfamily J member 12; Potassium inwardly rectifying channel subfamily J member 12; Potassium inwardly rectifying channel,subfamily J inhibitor 1. |
| 研究领域 | 细胞生物 神经生物学 细胞膜受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse,Rat (predicted: Human) |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 49kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Kir2.2: 351-433/433 <Cytoplasmic> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. Subcellular Location: Membrane. Similarity: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily. SWISS: Q14500 Gene ID: 3768 Database links: Entrez Gene: 100131509 Human Entrez Gene: 100290070 Human Entrez Gene: 3768 Human Entrez Gene: 16515 Mouse Omim: 602323 Human SwissProt: Q14500 Human SwissProt: P52187 Mouse Unigene: 200629 Human Unigene: 4970 Mouse Unigene: 10406 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
