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KIF22 Rabbit pAb (bs-17049R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-17049R
英文名称 KIF22 Rabbit pAb
中文名称 驱动蛋白家族成员22抗体
别    名 A 328A3.2; KID; KIF 22; kif22; KIF22_HUMAN; Kinesin family member 22; Kinesin like 4; Kinesin like DNA binding protein; Kinesin like DNA binding protein pseudogene; Kinesin like protein 4; Kinesin like protein KIF22; Kinesin-like DNA-binding protein; Kinesin-like protein 4; Kinesin-like protein KIF22; KNSL 4; KNSL4; OBP 1; OBP 2; OBP; OBP1; OBP2; Origin of plasmid DNA replication binding protein; OriP binding protein; OTTHUMP00000123406.  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Zebrafish,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 73 kDa
检测分子量
细胞定位 细胞核 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIF22: 221-320/665 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA.

Subcellular Location:
Nucleus. Cytoplasm; cytoskeleton.

Post-translational modifications:
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.

Similarity:
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain.

SWISS:
Q14807

Gene ID:
3835

Database links:

Entrez Gene: 3835 Human

Entrez Gene: 110033 Mouse

Entrez Gene: 293502 Rat

Omim: 603213 Human

SwissProt: Q14807 Human

SwissProt: Q3V300 Mouse

SwissProt: Q5I0E8 Rat

Unigene: 612151 Human

Unigene: 286488 Mouse

Unigene: 8601 Rat



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