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KAP3.3 Rabbit pAb (bs-16851R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-16851R
英文名称 KAP3.3 Rabbit pAb
中文名称 角蛋白相关蛋白KAP3.3抗体
别    名 KRTAP3-3High sulfur keratin-associated protein 3.3; KAP3.3; Keratin-associated protein 3-3; Keratin-associated protein 3.3; KRA33_HUMAN; Krtap3-3; KRTAP3.3.  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human,Mouse,Rat,Cow)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KAP3.3 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]

Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

Tissue Specificity:
Localized to the upper cortex of the hair shaft.

Similarity:
Belongs to the KRTAP type 3 family.

SWISS:
Q9BYR6

Gene ID:
85293

Database links:

Entrez Gene: 768045 Cow

Entrez Gene: 85293 Human

Entrez Gene: 66380 Mouse

Entrez Gene: 363678 Rat

SwissProt: Q24JX9 Cow

SwissProt: Q9BYR6 Human

SwissProt: Q9D7P0 Mouse

Unigene: 662759 Human

Unigene: 30539 Mouse



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