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Rabbit Anti-TRAPPC6A  antibody (bs-16587R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-16587R
英文名称 TRAPPC6A
中文名称 TRAPPC6A蛋白抗体
别    名 1810073E21Rik; 4930519D19Rik; AI480686; HSPC289; MGC117907; mhyp; OTTMUSP00000025165; OTTMUSP00000025166; rCG_54352; RGD1309160; TPC6A_HUMAN; Trafficking protein particle complex 6A; Trafficking protein particle complex subunit 6A; TRAPP complex subunit 6A; TRAPPC6A; TRS33.  
Specific References  (1)     |     bs-16587R has been referenced in 1 publications.
[IF=3.687] Yuan FH et al. microRNA‐30a inhibits the liver cell proliferation and promotes cell apoptosis through the JAK/STAT signaling pathway by targeting SOCS‐1 in rats with sepsis. J Cell Physiol. 2019 Apr 10.  WB ;  Rat.  
研究领域 细胞生物  信号转导  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Dog,Horse)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 18kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRAPPC6A: 21-100/159 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 TRAPPC6A is a 159 amino acid protein that localizes to the Golgi apparatus and endoplasmic reticulum. Belonging to the TRAPP small subunits family and the BET3 subfamily, TRAPPC6A may play a role in vesicular transport during the biogenesis of melanosomes. TRAPPC6A is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor. TRAPPC6A exists as a heterodimer with TRAPPC3 and undergoes alternative splicing to produce two isoforms. TRAPPC6A is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a variety of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).

Function:
May play a role in vesicular transport during the biogenesis of melanosomes.

Subunit:
Part of the multisubunit TRAPP (transport protein particle) complex. Heterodimer with TRAPPC3. The heterodimer TRAPPC3-TRAPPC6A interacts with TRAPPC2L. Interacts with TRAPPC2L.

Subcellular Location:
Golgi apparatus; cis-Golgi network. Endoplasmic reticulum.

Similarity:
Belongs to the TRAPP small subunits family. BET3 subfamily.

SWISS:
O75865

Gene ID:
79090

Database links:

Entrez Gene: 79090 Human

Omim: 610396 Human

SwissProt: O75865 Human

Unigene: 466929 Human



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