产品编号 | bs-16566R |
英文名称 | TRAM2 |
中文名称 | 相关易位膜蛋白2抗体 |
别 名 | C330003D03Rik; KIAA0057; MGC25725; OTTHUMP00000016607; TRAM like protein; Tram2; TRAM2_HUMAN; Translocating chain associating membrane protein 2; Translocating chain-associated membrane protein 2; Translocation associated membrane protein 2. |
研究领域 | 细胞生物 信号转导 跨膜蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 43kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TRAM2: 51-150/370 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.[supplied by OMIM, Jul 2004] Function: Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Subcellular Location: Membrane. Similarity: Belongs to the TRAM family. Contains 1 TLC (TRAM/LAG1/CLN8) domain. SWISS: Q15035 Gene ID: 9697 Database links: Entrez Gene: 9697 Human Entrez Gene: 100730382 Guinea pig Entrez Gene: 100069225 Horse Entrez Gene: 170829 Mouse Entrez Gene: 406344 Zebrafish Omim: 608485 Human SwissProt: Q15035 Human SwissProt: Q924Z5 Mouse Unigene: 520182 Human Unigene: 185680 Mouse Unigene: 273241 Mouse |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |