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Rabbit Anti-ZSCAN4  antibody (bs-16399R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-16399R
英文名称 ZSCAN4
中文名称 ZSCAN4蛋白抗体
别    名 FLJ35105; MGC126787; MGC126789; Zinc finger and SCAN domain containing 4; Zinc finger and SCAN domain containing protein 4; Zinc finger and SCAN domain-containing protein 4; Zinc finger protein 494; ZNF 494; ZNF494; ZSCA4_HUMAN; ZSCAN4.  
研究领域 细胞生物  转运蛋白  锌指蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 49kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZSCAN4: 331-433/433 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 20336070]).[supplied by OMIM, May 2010]

Function:
Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells.

Subcellular Location:
Nucleus. Chromosome > telomere.

Similarity:
Contains 4 C2H2-type zinc fingers.
Contains 1 SCAN box domain.

SWISS:
Q8NAM6

Gene ID:
201516

Database links:

Entrez Gene: 201516 Human

Omim: 613419 Human

SwissProt: Q8NAM6 Human

Unigene: 469663 Human



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