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GPHB5 Rabbit pAb (bs-16275R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-16275R
英文名称 GPHB5 Rabbit pAb
中文名称 糖蛋白激素β亚基5抗体
别    名 CGH; Glycoprotein hormone beta 5; GPHB5_HUMAN; Glycoprotein hormone beta 5 precursor; Glycoprotein hormone beta subunit; GPB5; Thyrostimulin subunit beta; ZLUT1.  
研究领域 细胞生物  信号转导  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat (predicted: Human,Mouse,Pig,Sheep,Cow,Dog,Horse,Gorilla,Xenopus tropicalis,Elephant)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 12 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPHB5: 25-100/130 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 GPHB5 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002 [PubMed 12089349]).[supplied by OMIM, Mar 2008]

Function:
GPHB5 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family. Corticotroph-derived glycoprotein hormone (CGH), also referred to as thyrostimulin, is a noncovalent heterodimer of glycoprotein hormone alpha 2 (GPHA2) and glycoprotein hormone beta 5 (GPHB5).

Subunit:
Heterodimer with GPHA2.

Subcellular Location:
Secreted

Tissue Specificity:
Highly expressed in brain and at low levels in pituitary. Also found in retina, testis and skin but not in pancreas, parotid, kidney, stomach, liver, colon, small intestine, thyroid, brain or adrenal gland. In pituitary, colocalizes with ACTH, suggesting that it is located in corticotrophs.

Post-translational modifications:
N-glycosylated.

Similarity:
Belongs to the glycoprotein hormones subunit beta family.

SWISS:
Q86YW7

Gene ID:
122876

Database links:

Entrez Gene: 122876 Human

Entrez Gene: 217674 Mouse

Omim: 609652 Human

SwissProt: Q86YW7 Human

SwissProt: Q812B2 Mouse

Unigene: 375028 Human



产品图片
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Ant
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