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Rabbit Anti-FXL19  antibody (bs-16201R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-16201R
英文名称 FXL19
中文名称 FXL19蛋白抗体
别    名 F-box and leucine-rich repeat protein 19; F-box/LRR-repeat protein 19; FBL19; Fbxl19; FXL19_HUMAN; JHDM1C; Jumonji C domain containing histone demethylase 1C.  
研究领域 细胞生物  跨膜蛋白  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 76kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FXL19: 401-500/694 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Subunit:
Directly interacts with SKP1 and CUL1 (By similarity).

Similarity:
Contains 1 CXXC-type zinc finger.
Contains 1 F-box domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 PHD-type zinc finger.

SWISS:
Q6PCT2

Gene ID:
54620

Database links:

Entrez Gene: 54620 Human

Entrez Gene: 233902 Mouse

Entrez Gene: 308999 Rat

GenBank: BC059173 Human

Omim: 609085 Human

SwissProt: Q6PCT2 Human

SwissProt: Q6PB97 Mouse

Unigene: 152149 Human



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