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FAM57B Rabbit pAb (bs-16005R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-16005R
英文名称 FAM57B Rabbit pAb
中文名称 FAM57B蛋白抗体
别    名 FA57B_HUMAN; Protein FAM57B.  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 31 kDa
检测分子量
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FAM57B: 21-120/559 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The FAM57B gene product has been provisionally designated FAM57B pending further characterization.

Subcellular Location:
Membrane.

Similarity:
Contains 1 TLC (TRAM/LAG1/CLN8) domain.

SWISS:
Q71RH2

Gene ID:
83723

Database links:

Entrez Gene: 83723 Human

Entrez Gene: 785988 Cow

Entrez Gene: 100066097 Horse

Entrez Gene: 68952 Mouse

Entrez Gene: 293493 Rat

Omim: 615175 Human

SwissProt: Q71RH2 Human

SwissProt: Q7TNV1 Mouse

Unigene: 558560 Human

Unigene: 440393 Mouse

Unigene: 128103 Rat



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