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GRP Rabbit pAb (bs-10631R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-10631R
英文名称 GRP Rabbit pAb
中文名称 半乳糖凝集素相关蛋白GRP抗体
别    名 LGALSL; LEGL_HUMAN; Galectin-related protein; Lectin galactoside-binding-like protein; HSPC159.  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Pig,Dog,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 kDa
检测分子量
细胞定位 细胞外基质 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GRP: 1-100/172 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and also play a role in tumor progression, pre-mRNA splicing and apoptosis. The Galectin-related protein (GRP), also designated HSPC159, is a 172 amino acid protein that contains one galectin domain. However, HSPC159 does not appear to bind carbohydrates or lactose because the critical residues required for binding are not conserved. The gene encoding HSPC159 maps to human chromosome 2, which consists of 237 million bases and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2, including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome.

Function:
Does not bind lactose, and may not bind carbohydrates.

Subunit:
Monomer (Probable).

Similarity:
Contains 1 galectin domain.

SWISS:
Q3ZCW2

Gene ID:
29094

Database links:

Entrez Gene: 470387 Chimpanzee

Entrez Gene: 516629 Cow

Entrez Gene: 101141454 Gorilla

Entrez Gene: 29094 Human

Entrez Gene: 216551 Mouse

Entrez Gene: 360983 Rat

SwissProt: Q3ZCW2 Human

SwissProt: Q8VED9 Mouse

SwissProt: Q5R5K6 Orangutan

Unigene: 372208 Human



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