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CHST9 Rabbit pAb (bs-13940R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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产品编号 bs-13940R
英文名称 CHST9 Rabbit pAb
中文名称 碳水化合物磺基转移酶8抗体
别    名 Carbohydrate(N acetylgalactosamine 4 0) sulfotransferase 8; Carbohydrate sulfotransferase 8; CHST 8; GalNAc 4 O sulfotransferase 1; GalNAc 4 ST1; CHST9_HUMAN; GalNAc4ST 1; GalNAc4ST; GALNAC4ST1; N acetylgalactosamine 4 O sulfotransferase 1; N acetylgalactosamine 4 O sulfotransferase.  
研究领域 信号转导  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human (predicted: Mouse,Rabbit,Horse)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 52 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CHST9: 351-443/443 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Sulfate groups on carbohydrates confer highly specific functions to glycoproteins, glycolipids, and proteoglycans, and are critical for cell-cell interaction, signal transduction, and embryonic development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2011]

Function:
Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. Isoform 2, but not isoform 1, is active toward chondroitin.

Subcellular Location:
Secreted and Golgi apparatus membrane.

Tissue Specificity:
Highly expressed in trachea. Also expressed in fetal lung, adult pancreas, testis and salivary gland. Expressed at low level in pituitary gland, apex of the heart, adult lung, prostate and mammary gland. Weakly or not expressed in heart, liver and spinal cord.

Similarity:
Belongs to the sulfotransferase 2 family.

SWISS:
Q7L1S5

Gene ID:
83539

Database links:

Entrez Gene: 83539 Human

Entrez Gene: 71367 Mouse

Omim: 610191 Human

SwissProt: Q7L1S5 Human

SwissProt: Q76EC5 Mouse

Unigene: 44584 Human

Unigene: 706552 Human

Unigene: 329304 Mouse



产品图片
Sample: HepG2 (human)Cell Lysate at 40 ug MDA-MB-231 (human)Cell Lysate at 40 ug Primary: Anti-CHST9(bs-13940R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD
Sample: 293T (human)Cell Lysate at 40 ug Primary: Anti-CHST9(bs-13940R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD
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