| 产品编号 | bs-13659R |
| 英文名称 | PACSIN3 Rabbit pAb |
| 中文名称 | 胞浆蛋白PACSIN3抗体 |
| 别 名 | Endophilin 1; Endophilin I; FLJ17861; OTTHUMP00000234262; OTTHUMP00000234263; OTTHUMP00000234264; PACN3_HUMAN; Pacsin3; Protein kinase C and casein kinase substrate in neurons 3; Protein kinase C and casein kinase substrate in neurons protein 3; SDPIII; SH3 domain containing protein 6511; SH3 domain-containing protein 6511; syndapin III; |
| 研究领域 | 细胞生物 神经生物学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Horse) |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 48 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PACSIN3: 251-350/424 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity). Function: May play a role in vesicle formation and transport. Subcellular Location: Cytoplasm. Cell membrane. Detected at the inner aspect of the plasma membrane in cells or myotubes. Tissue Specificity: Expressed in heart and skeletal muscle, lung, kidney, adrenal gland and placenta. Post-translational modifications: Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). Similarity: Belongs to the PACSIN family. Contains 1 FCH domain. Contains 1 SH3 domain. SWISS: Q9UKS6 Gene ID: 29763 Database links: Entrez Gene: 29763 Human Entrez Gene: 80708 Mouse Omim: 606513 Human SwissProt: Q9UKS6 Human SwissProt: Q99JB8 Mouse Unigene: 334639 Human |
| 产品图片 |
Sample:A431 (Human)Cell Lysate at 40 ug
Primary: Anti-PACSIN3(bs-13659R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 48kD
Observed band size: 50kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
