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Rabbit Anti-CCL26 antibody (bs-15512R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-15512R
英文名称 Rabbit Anti-CCL26 antibody
中文名称 趋化因子26/嗜酸粒细胞趋化蛋白3抗体
别    名 C-C motif chemokine 26; CC chemokine IMAC; CCL 26; CCL26_HUMAN; Chemokine (C C motif) ligand 26; Eotaxin-3; Eotaxin 3; Eotaxin3; IMAC; Macrophage inflammatory protein 4-alpha; MIP 4a; MIP 4alpha; MIP-4-alpha; MIP4a; MIP4alpha; SCYA 26; SCYA26; Small inducible cytokine A26; Small inducible cytokine subfamily A (Cys Cys) member 26; Small inducible cytokine subfamily A member 26; Small-inducible cytokine A26; Thymic stroma chemokine 1; Thymic stroma chemokine-1; TSC 1; TSC-1; TSC1.  
Specific References  (1)     |     bs-15512R has been referenced in 1 publications.
[IF=2.3] Andrea Sit. et al. CCAD or eCRS: Defining Eosinophilic Subpopulations in Chronic Rhinosinusitis. AM J RHINOL ALLERGY. ;():  IHC ;  Human.  
研究领域 细胞生物  免疫学  细胞凋亡  趋化因子  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,Flow-Cyt=1ug/test,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 8kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CCL26: 51-94/94 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009]

Function:
Chemotactic for eosinophils and basophils. Binds to CCR3.

Subunit:
Monomer.

Subcellular Location:
Secreted.

Tissue Specificity:
Ubiquitously expressed at low levels in various tissues including heart and ovary.

Similarity:
Belongs to the intercrine beta (chemokine CC) family.

SWISS:
Q9Y258

Gene ID:
10344

Database links:

Entrez Gene: 10344 Human

Entrez Gene: 541307 Mouse

Omim: 604697 Human

SwissProt: Q9Y258 Human

Unigene: 131342 Human

Unigene: 376459 Mouse




产品图片
Paraformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CCL26) Polyclonal Antibody, Unconjugated (bs-15512R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (human cervical carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CCL26) Polyclonal Antibody, Unconjugated (bs-15512R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Blank control:U-2OS. Primary Antibody (green line): Rabbit Anti-CCL26 antibody (bs-15512R) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test. Protocol The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with 20% PBST for 20 min at room temperature. The cells were then incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
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