产品编号 | bs-10383R |
英文名称 | FGFR substrate 3 |
中文名称 | 纤维母细胞生长因子受体底物3抗体 |
别 名 | FGFR signalling adaptor SNT2; FGFR substrate 3; Fibroblast growth factor receptor substrate 3; FRS2 beta; FRS2B; FRS3; FRS3 protein; MGC17167; SNT 2; Suc1 associated neurotrophic factor target 2 (FGFR signalling adaptor); Suc1 associated neurotrophic factor target 2; FRS3_HUMAN; FGFR-signaling adaptor SNT2; Suc1-associated neurotrophic factor target 2; SNT-2. |
研究领域 | 信号转导 生长因子和激素 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human,Mouse,Rat,Cow,Rabbit,Sheep) |
产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 54kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FGFR substrate 3: 401-492/492 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. [provided by RefSeq, Jul 2008]. Function: Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. Subunit: Binds NTRK1. Binds FGFR1, NGFR, GRB2, PTPN11 and ERK2. Subcellular Location: Membrane; Lipid-anchor. Tissue Specificity: Phosphorylated by ULK2 in vitro. Phosphorylated on tyrosine residues upon stimulation by BFGF or NGFB. Similarity: Contains 1 IRS-type PTB domain. SWISS: O43559 Gene ID: 10817 Database links: Entrez Gene: 10817 Human Entrez Gene: 107971 Mouse Omim: 607744 Human SwissProt: O43559 Human SwissProt: Q91WJ0 Mouse Unigene: 194208 Human Unigene: 34398 Rat |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |