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HCP5 Rabbit pAb (bs-15429R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-15429R
英文名称 HCP5 Rabbit pAb
中文名称 血红素转运蛋白5抗体
别    名 HLA class I histocompatibility antigen protein P5; HLA complex protein P5; Protein P5 1; HCP5_HUMAN.  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 14 kDa
检测分子量
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HCP5: 1-80/132 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 HCP5 is a region present on chromosome 6p21.3 that is characterized by multiple duplicated gene families. HCP5 (HLA class I histocompatibility antigen protein P5), also known as P5-1, is a 132 amino acid protein that is encoded by a gene mapping to human chromosome 6p21.33. Localizing within the MHC class I region, HCP5 is not structurally related to other MHC class I genes, but does have high sequence similarity with HERV-L and HERV-16. HCP5 also has high sequence homology to retroviral Pol genes, making it a possible candidate for interaction with HIV-1 through an antisense mechanism that prevents retrovirus transcription. Single-nucleotide polymorphisms (SNPs) to the region of the HCP5 gene that corresponds with HLA-B has been linked to a lower HIV-1 viral set point. HCP5 is highly expressed in lymphoid tissues, spleen and activated lymphocytes, as well as B-cell and natural killer (NK) cell lines.

Tissue Specificity:
Expressed in lymphoid tissues; Detected in spleen as well as in B-cell lines, NK cell lines and activated lymphocytes.

SWISS:
Q6MZN7

Gene ID:
10866

Database links:

Entrez Gene: 10866 Human

Omim: 604676 Human

SwissProt: Q6MZN7 Human

Unigene: 654480 Human



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