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Rabbit Anti-ENTPD1/CD39  antibody (bs-15383R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-15383R
英文名称 ENTPD1/CD39
中文名称 CD39/ENTPD1抗体
别    名 ENTP1_HUMAN; Ectonucleoside triphosphate diphosphohydrolase 1; EC:3.6.1.5; SPG64; ATPDase; NTPDase-1; NTPDase 1; CD39; CD 39; Ecto-ATP diphosphohydrolase 1 (Ecto-ATPDase 1; Ecto-ATPase 1); Ecto-apyrase; Lymphoid cell activation antigen;   
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human (predicted: Mouse,Rat,Pig,Cow,Sheep)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 58kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD39/entpd1 : 101-200/510 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

Function:
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.

Subunit:
Homodimer; disulfide-linked (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).

Tissue Specificity:
Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Isoform 1 and isoform 3 are present in both placenta and umbilical vein, whereas isoform 2 is present in placenta only.

Post-translational modifications:
The N-terminus is blocked.
Palmitoylated in the N-terminal part.

Similarity:
Belongs to the GDA1/CD39 NTPase family.

SWISS:
P49961

Gene ID:
953

Database links:

Entrez Gene: 953 Human

Entrez Gene: 12495 Mouse

Entrez Gene: 64519 Rat

Omim: 601752 Human

SwissProt: P49961 Human

SwissProt: P55772 Mouse

SwissProt: P97687 Rat

Unigene: 576612 Human

Unigene: 2824 Mouse

Unigene: 17491 Rat



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