| 产品编号 | bs-13315R |
| 英文名称 | Gcn1l1 Rabbit pAb |
| 中文名称 | 广泛控制氨基酸合成1样蛋白1抗体 |
| 别 名 | GCN1; GCN1(general control of amino acid synthesis yeast homolog) like; GCN1(general control of amino acid synthesis 1 yeast) like 1; GCN1 general control of amino acid synthesis 1 like 1; GCN1 general control of amino acid synthesis 1 like 1(yeast); GCN1 like protein 1; GCN1L; HsGCN1; GCN1L_HUMAN. |
| 研究领域 | 细胞生物 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human,Mouse,Rat,Cow,Dog,Horse) |
| 产品应用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 293 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Gcn1l1: 751-850/2671 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
GCN1L1 is a 2,671 amino acid protein that is ubiquitously expressed and belongs to the GCN1 family. Functioning as a translation activator, GCN1L1 interacts with IMPACT to regulproteinate GCN2 kinase activity. GCN1L1 contains 24 HEAT repeats and is encoded by a gene that maps to human chromosome 12q24.23. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders. Function: Gcn1l1 acts as a translation activator which mediates translational control and performs an EF3-related function on the ribosome by regulating GCN2 protein kinase (EIF2AK1-4) activity. Subunit: Interacts with IMPACT; prevents the interaction with GCN2 protein kinase (EIF2AK1-4) (By similarity). Subcellular Location: Cytoplasmic Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the GCN1 family. Contains 24 HEAT repeats. SWISS: Q92616 Gene ID: 10985 Database links: Entrez Gene: 10985 Human Entrez Gene: 231659 Mouse Omim: 605614 Human SwissProt: Q92616 Human SwissProt: E9PVA8 Mouse SwissProt: Q8BIX2 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
