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Rabbit Anti-GANC  antibody (bs-13279R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-13279R
英文名称 GANC
中文名称 α-葡萄糖苷酶C抗体
别    名 Neutral alphaglucosidase C; Ganc; GANC_HUMAN; Glucosidase alpha neutral C; MGC138256; Neutral alpha glucosidase C; Neutral alpha-glucosidase C; Neutral alphaglucosidase C.  
Specific References  (1)     |     bs-13279R has been referenced in 1 publications.
[IF=3.144] Wang,et al.Oat globulin peptides regulate antidiabetic drug targets and glucose transporters in Caco-2 cells.(2018) Journal of Functional Foods. 42:12-20.  WB ;  Human.  
研究领域 肿瘤  细胞生物  信号转导  糖尿病  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Horse)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 104kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GANC/Neutral alphaglucosidase C: 31-130/914 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 A key enzyme in glycogen degradation and metabolism, GANC (glucosidase, α neutral C) is a 914 amino acid protein with α-glucosidase activity that belongs to the glycosyl hydrolase 31 family and hydrolyzes non-reducing, terminal 1,4-linked α-D-glucose residues and releases α-D-glucose. The gene encoding GANC maps to human chromosome 15q15.1, a region associated with susceptibility to non-insulin-dependent (type 2) diabetes mellitus, a disease characterized by high blood glucose levels. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Function:
Has alpha-glucosidase activity.

Similarity:
Belongs to the glycosyl hydrolase 31 family.

SWISS:
Q8TET4

Gene ID:
2595

Database links:

Entrez Gene: 2595 Human

Omim: 104180 Human

SwissProt: Q8TET4 Human

Unigene: 143261 Human

Unigene: 730806 Human



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