| 产品编号 | bs-13259R |
| 英文名称 | GABA Transporter 2 Rabbit pAb |
| 中文名称 | γ氨基丁酸运载蛋白2抗体 |
| 别 名 | GABA transport protein; GAT 2; GAT-2; GAT2; Solute carrier family 6(Neurotransmitter transporter, GABA), member 13; S6A13_HUMAN. |
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Specific References (1) | bs-13259R has been referenced in 1 publications.
[IF=2.27] Tai, Tran Tien, et al. "Neurotransmitter transporter family including SLC6A6 and SLC6A13 contributes to the 5‐aminolevulinic acid (ALA)‐induced accumulation of protoporphyrin IX and photo‐damage, through uptake of ALA by cancerous cells." Photochemistry and Photobiology (2014). IHC-P ; Human.
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| 研究领域 | 细胞生物 神经生物学 细胞膜受体 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse) |
| 产品应用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 68 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GABA Transporter 2/GAT-2: 131-230/602 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
GABA is a major inhibitory neurotransmitter and the GABAergic transmission is terminated by the rapid Na+/Cl-dependent uptake of through GABA transporters. There are multiple subtypes of GABA transporters (GAT1, GAT2, GAT3; and betaine GABA transporter (BGT-1). There is ~50% homology between each subtypes. GAT1 and GAT3 have been detected in various parts of the brain while GAT2 is found in many tissues. It appears that GAT1 and GAT3 are involved in distinct GABAergic transmission while GAT2 may be important in non-neural functions. GAT2 is a gamma-amino butyric acid (GABA) transporter. It is a 602 amino acid (85kDa) transmembrane protein. Function: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in brain, kidney, lung, liver and testis. Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily. SWISS: Q9NSD5 Gene ID: 6540 Database links: Entrez Gene: 6540 Human Entrez Gene: 14412 Mouse SwissProt: Q8TCC2 Human SwissProt: Q9NSD5 Human SwissProt: P31649 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
