产品编号 | bs-13060R |
英文名称 | EFS |
中文名称 | 对接蛋白EFS抗体 |
别 名 | CAS3; CASS3; EFS1; EFS2; Embryonal Fyn associated substrate; HEFS; SIN; EFS_HUMAN. |
研究领域 | 细胞生物 细胞粘附分子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human,Mouse,Rat,Pig,Cow,Sheep) |
产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 59kDa |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human EFS: 201-300/561 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
EFS is a docking protein which plays a pivotal role for cell adhesion-related intracellular tyrosine kinase signaling, where it may serve as an activator of SRC and is known to interat with the SH3 domain of FYN and with CRK, SRC, and YES. Function: Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity). Subcellular Location: Cytoplasm Tissue Specificity: The protein has been detected in lung and placenta. Post-translational modifications: Phosphorylated on multiple tyrosine residues. Phosphorylated on tyrosines by FYN and SRC (By similarity). Similarity: Belongs to the CAS family. Contains 1 SH3 domain. SWISS: O43281 Gene ID: 10278 Database links: Entrez Gene: 10278 Human Entrez Gene: 13644 Mouse Omim: 609906 Human SwissProt: O43281 Human SwissProt: Q64355 Mouse |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |