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Rabbit Anti-phospho-MYB (Ser532)  antibody (bs-12917R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-12917R
英文名称 phospho-MYB (Ser532)
中文名称 磷酸化转录激活因子MYB抗体
别    名 c-Myb (phospho S532); p-c-Myb (phospho S532); Avian myeloblastosis viral (v-myb) oncogene homolog; C myb; c-Myb; MYB_HUMAN; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog.  
产品类型 磷酸化抗体 
研究领域 肿瘤  细胞生物  染色质和核信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 84kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human MYB around the phosphorylation site of Ser532: VE(p-S)PT 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Function:
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Subcellular Location:
Nucleus.

Post-translational modifications:
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.
Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.

Similarity:
Contains 3 HTH myb-type DNA-binding domains.

SWISS:
P10242

Gene ID:
4602

Database links:

Entrez Gene: 317776 Cow

Entrez Gene: 4602 Human

Entrez Gene: 17863 Mouse

Entrez Gene: 498982 Rat

Omim: 189990 Human

SwissProt: P46200 Cow

SwissProt: P10242 Human

SwissProt: P06876 Mouse

Unigene: 606320 Human

Unigene: 52109 Mouse



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