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Rabbit Anti-FLRT3  antibody (bs-12363R)  
~~~促销代码KT202411~~~
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说明书: 50ul  100ul  
50ul/1180.00元
100ul/1980.00元
大包装/询价

产品编号 bs-12363R
英文名称 Rabbit Anti-FLRT3  antibody
中文名称 富含亮氨酸跨膜纤连蛋白3抗体
别    名 FLRT3_HUMAN; Leucine-rich repeat transmembrane protein FLRT3; KIAA1469; Fibronectin-like domain-containing leucine-rich transmembrane protein 3; UNQ856/PRO1865;  
研究领域 发育生物学  信号转导  干细胞  细胞分化  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat (predicted: Human)
产品应用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 70kDa
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FLRT3 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 FLRT3 is a 649 amino acid single-pass type I membrane protein that contains one fibronectin type-III domain and ten leucine-rich repeats and belongs to the fibronectin leucine rich transmembrane protein (FLRT) family. Expressed in heart, liver, lung, kidney, pancreas, brain, placenta and skeletal muscle, FLRT3 is thought to be involved in receptor signaling events and may play a role in both cell adhesion neurite outgrowth. Defects in the gene encoding mouse FLRT3 may lead to ventral closure, headfold fusion and endoderm migration defects, suggesting that FLRT3 is important for proper cell differentiation and development. FLRT3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 20.

Function:
May have a function in cell adhesion and/or receptor signaling.

Subcellular Location:
Membrane; Single-pass type I membrane protein (Probable).

Tissue Specificity:
Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.

Similarity:
Contains 1 fibronectin type-III domain.
Contains 10 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

SWISS:
Q9NZU0

Gene ID:
23767

Database links:

Entrez Gene: 428552 Chicken

Entrez Gene: 23767 Human

Entrez Gene: 71436 Mouse

Entrez Gene: 366205 Rat

SwissProt: F1NUK7 Chicken

SwissProt: Q9NZU0 Human

SwissProt: B1H234 Rat



产品图片
Sample: Lane 1: Rat Cerebrum tissue lysates Lane 2: Rat Lung tissue lysates Primary: Anti-FLRT3 (bs-12363R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 70 kDa Observed band size: 73 kDa
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