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Rabbit Anti-FLRT1  antibody (bs-12361R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-12361R
英文名称 FLRT1
中文名称 富含亮氨酸跨膜纤连蛋白1抗体
别    名 Fibronectin-like domain containing leucine rich transmembrane protein 1; Fibronectin-like domain-containing leucine-rich transmembrane protein 1; FLRT1; FLRT1_HUMAN; Leucine rich repeat transmembrane protein FLRT1; Leucine-rich repeat transmembrane protein FLRT1.  
研究领域 细胞生物  发育生物学  信号转导  细胞粘附分子  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Chicken,Pig,Cow,Rabbit,Sheep)
产品应用 WB=1:500-2000, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 69kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FLRT1: 301-400/646 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. FLRT1 (fibronectin leucine rich transmembrane protein 1) is a 646 amino acid single-pass type I membrane protein that contains one fibronectin type-III domain and ten LRR repeats. Expressed in kidney and brain, FLRT1 is thought to play a role in cell adhesion and receptor signaling. FLRT1 shares similarity with FLRT2 and FLRT3 and is subject to post-translational N-glycosylation. The gene encoding FLRT1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.

Function:
May have a function in cell adhesion and/or receptor signaling.

Subcellular Location:
Membrane.

Tissue Specificity:
Expressed in kidney and brain.

Post-translational modifications:
N-glycosylated.

Similarity:
Contains 1 fibronectin type-III domain.
Contains 10 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

SWISS:
Q9NZU1

Gene ID:
23769

Database links:

Entrez Gene: 23769 Human

Entrez Gene: 396184 Mouse

Entrez Gene: 499308 Rat

Omim: 604806 Human

SwissProt: Q9NZU1 Human

SwissProt: Q6RKD8 Mouse

Unigene: 584876 Human

Unigene: 386930 Mouse



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