产品编号 | bs-12352R |
英文名称 | GSC Rabbit pAb |
中文名称 | 同源盒蛋白GSC抗体 |
别 名 | Goosecoid; goosecoid homeobox; GSC; GSC2; GSC_HUMAN; homeobox protein goosecoid-like; homeobox protein goosecoid-2; Homeobox protein goosecoid; GSC 2; GSCL; Homeobox protein goosecoid 2; Homeobox protein goosecoid like. |
研究领域 | 细胞生物 发育生物学 信号转导 干细胞 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Rat (predicted: Human,Mouse,Rabbit,Pig,Sheep,Cow,Zebrafish,Chicken,Dog) |
产品应用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 28 kDa |
检测分子量 | |
细胞定位 | 细胞核 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from Human GSC: 151-257/257 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
Goosecoid is a homeodomain transcription factor with DNA binding specificity identical to that of the anterior morphogen 'bicoid' in Drosophila.During mouse embryogenesis, GSC influences development of the lower mandible and its associated musculature, including the tongue, the nasal cavity, and the nasal pits, as well as components of the inner ear and the external auditory meatus. The GSC gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. Function: Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring. Subcellular Location: Nucleus. Similarity: Belongs to the paired homeobox family. Bicoid subfamily. Contains 1 homeobox DNA-binding domain. SWISS: O15499 Gene ID: 2928 Database links: Entrez Gene: 2928 Human Entrez Gene: 195333 Mouse SwissProt: O15499 Human SwissProt: P56916 Mouse |
产品图片 |
Tissue/cell: Rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat se
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1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |