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KCNG1 Rabbit pAb (bs-12174R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-12174R
英文名称 KCNG1 Rabbit pAb
中文名称 电压门控性钾通道蛋白亚基kv6.1抗体
别    名 K13; KCNG; kH2; KV6.1; Potassium voltage gated channel subfamily G; Potassium voltage gated channel subfamily G member 1; Voltage gated potassium channel subunit Kv6.1; KCNG1_HUMAN.  
研究领域 细胞生物  神经生物学  通道蛋白  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,GuineaPig,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 58 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNG1: 401-500/513 <Cytoplasmic>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008].

Function:
KCNG1 is a member of the potassium channel, voltage-gated, subfamily G. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene is abundantly expressed in skeletal muscle. Alternative splicing results in at least two transcript variants encoding distinct isoforms.

Subunit:
Heterotetramer of potassium channel proteins (By similarity).

Subcellular Location:
Membrane; multi-pass membrane protein

Tissue Specificity:
Detected in brain and placenta, and at much lower levels in kidney and pancreas.

Similarity:
Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.1/KCNG1 sub-subfamily.

SWISS:
Q9UIX4

Gene ID:
3755

Database links:

Entrez Gene: 3755 Human

Entrez Gene: 241794 Mouse

Entrez Gene: 296395 Rat

Omim: 603788 Human

SwissProt: Q9UIX4 Human

SwissProt: A2BDX4 Mouse

Unigene: 118695 Human

Unigene: 91149 Rat



产品图片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; A
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