| 产品编号 | bs-12140R |
| 英文名称 | DLGAP4 |
| 中文名称 | PSD95结合蛋白4抗体 |
| 别 名 | DLGAP4; DAP 4; DAP-4; DAP4; Discs, large (Drosophila) homolog associated protein 4; Disks large associated protein 4; Disks large-associated protein 4; DLGAP4; DLGP4_HUMAN; DLP4; PSD 95/SAP90 binding protein 4; PSD-95/SAP90-binding protein 4; RP5-977B1.6; SAP90/PSD-95-associated protein 4; SAPAP 4; SAPAP-4; SAPAP4. |
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Specific References (1) | bs-12140R has been referenced in 1 publications.
[IF=4.996] Dong, Cairong. et al. DLGAP4 acts as an effective prognostic predictor for hepatocellular carcinoma and is closely related to tumour progression. SCI REP-UK. 2022 Nov;12(1):1-14 IHC ; Human.
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| 研究领域 | 神经生物学 通道蛋白 细胞膜受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse (predicted: Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig) |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 108kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SAPAP4/DLGAP4: 261-370/992 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP4 is a 992 amino acid protein that likely localizes to the postsynaptic membrane of neurons to enhance neuronal signaling. SAPAP4 could act as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP4, DLGAP4, maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception. Function: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Subunit: Interacts with DLG1 and DLG4/PSD-95 (By similarity). Subcellular Location: Membrane; Peripheral membrane protein (By similarity). Similarity: Belongs to the SAPAP family. SWISS: Q9Y2H0 Gene ID: 22839 Database links: Entrez Gene: 22839 Human Entrez Gene: 228836 Mouse SwissProt: Q9Y2H0 Human SwissProt: B1AZP2 Mouse Unigene: 249600 Human Unigene: 22094 Mouse Unigene: 11279 Rat |
| 产品图片 |
Sample:
Muscle (Mouse) Lysate at 40 ug Primary: Anti- DLGAP4(bs-12140R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 108 kD Observed band size: 108 kD |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
