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Rabbit Anti-KCTD8  antibody (bs-12087R)  
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-12087R
英文名称 Rabbit Anti-KCTD8  antibody
中文名称 钾离子通道多聚体结构域蛋白8抗体
别    名 BTB/POZ domain-containing protein KCTD8; KCTD8; KCTD8_HUMAN; Potassium channel tetramerisation domain containing 8.  
研究领域 神经生物学  信号转导  通道蛋白  细胞膜受体  G蛋白偶联受体  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 52 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCTD8: 381-473/473 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.

Function:
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).

Subunit:
Interacts as a tetramer with GABRB1 and GABRB2 (By similarity).

Subcellular Location:
Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse > postsynaptic cell membrane.

Similarity:
Contains 1 BTB (POZ) domain.

SWISS:
Q6ZWB6

Gene ID:
386617

Database links:

Entrez Gene: 386617 Human

Entrez Gene: 243043 Mouse

SwissProt: Q6ZWB6 Human

SwissProt: Q50H33 Mouse

Unigene: 479644 Human

Unigene: 234821 Mouse



产品图片
Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Cerebellum tissue lysates Lane 3: Mouse Muscle tissue lysates Lane 4: Rat Cerebrum tissue lysates Lane 5: Rat Cerebellum tissue lysates Lane 6: Rat Stomach tissue lysates Lane 7: Rat Muscle tissue lysates Primary: Anti-KCTD8 (bs-12087R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kDa Observed band size: 52 kDa
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