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AKAP7 Rabbit pAb (bs-11999R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-11999R
英文名称 AKAP7 Rabbit pAb
中文名称 蛋白激酶A锚定蛋白7抗体
别    名 A kinase(PRKA) anchor protein 7; A kinase anchor protein 18 kD; A Kinase Anchor Protein 7; A Kinase Anchor Protein 7 Isoform alpha; A kinase anchor protein 7 isoform beta; A kinase anchor protein 7 isoform gamma; A kinase anchor protein 7 isoforms alpha and beta; A kinase anchor protein 9 kDa; A Kinase Anchoring Protein 18; A-kinase anchor protein 18 kDa; A-kinase anchor protein 7 isoforms alpha and beta; AKA7A_HUMAN; AKAP 18; AKAP 7; AKAP-7 isoforms alpha and beta; AKAP15; AKAP18; Akap7; HGNC377; OTTHUMP00000040266; Protein kinase A anchoring protein 7; Protein kinase A anchoring protein 7 isoform alpha; Protein kinase A anchoring protein 7 isoform beta; Protein kinase A anchoring protein 7 isoform gamma; Protein kinase A anchoring protein 7 isoforms alpha/beta; Protein kinase A-anchoring protein 7 isoforms alpha/beta.  
研究领域 细胞生物  神经生物学  信号转导  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human,Rat (predicted: Mouse,Pig,Sheep,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 11.3 kDa
检测分子量
细胞定位 细胞核 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AKAP7: 31-80/104 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 A kinase (PRKA) anchor protein 7; A kinase anchor protein 18 kD; A Kinase Anchor Protein 7; A Kinase Anchor Protein 7 Isoform Alpha; A kinase anchor protein 7 isoform beta; A kinase anchor protein 7 isoform gamma; A kinase anchor protein 7 isoforms alpha and beta; A kinase anchor protein 9 kDa; A Kinase Anchoring Protein 18; A-kinase anchor protein 18 kDa; A-kinase anchor protein 7 isoforms alpha and beta; AKA7A_HUMAN; AKAP 18; AKAP 7; AKAP-7 isoforms alpha and beta; AKAP15; AKAP18; Akap7; HGNC377; OTTHUMP00000040266; Protein kinase A anchoring protein 7; Protein kinase A anchoring protein 7 isoform alpha; Protein kinase A anchoring protein 7 isoform beta; Protein kinase A anchoring protein 7 isoform gamma; Protein kinase A anchoring protein 7 isoforms alpha/beta; Protein kinase A-anchoring protein 7 isoforms alpha/beta.

Function:
Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel.

Subunit:
Binds cAMP-dependent protein kinase (PKA). Interacts with PRKCA; only the cytoplasmic form is capable of interacting with PRKCA.

Subcellular Location:
Apical cell membrane. Targeted predominantly to the apical membrane and Lateral cell membrane. Targeted predominantly to the lateral membrane.

Tissue Specificity:
Expressed in brain, heart, lung, pancreas and skeletal muscle.

SWISS:
Q9P0M2

Gene ID:
9465

Database links:

Entrez Gene: 9465 Human

Entrez Gene: 432442 Mouse

Entrez Gene: 361458 Rat

Omim: 604693 Human

SwissProt: O43687 Human

SwissProt: Q9P0M2 Human

SwissProt: O55074 Mouse

SwissProt: Q6JP77 Rat



产品图片
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-AKAP7 Polyclonal Antibody, Unconjugated(bs-11999R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Paraformaldehyde-fixed, paraffin embedded (Human breast carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (AKAP7) Polyclonal Antibody, Unconjugated (bs-11999R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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