| 产品编号 | bs-11921R |
| 英文名称 | GATAD1 |
| 中文名称 | 眼发育相关基因蛋白ODAG抗体 |
| 别 名 | ODAG; GATA zinc finger domain containing 1; Ocular development associated gene; GATA zinc finger domain-containing protein 1; ocular development-associated gene protein; GATAD1 protein; ocular development associated; ODAG; RG083M05.2; tcag7.279; GATD1_HUMAN. |
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Specific References (1) | bs-11921R has been referenced in 1 publications.
[IF=4.3] Ma, Xiaoling, et al. "Decreased expression and DNA methylation levels of GATAD1 in preeclamptic placentas." Cellular Signalling (2014). IHC-P ; Human.
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| 研究领域 | 细胞生物 神经生物学 信号转导 生长因子和激素 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep) |
| 产品应用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 29kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GATAD1/ODAG: 61-160/269 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] Function: ODAG (Ocular development-associated gene), a novel transcription factor located on chromosome 7, encodes a protein that may play a role in eye development. mRNA profiling in multiple human tissue indicates that ODAG is expressed in human CD56+ NK cells and thyroid tissue. Subunit: Component of a chromatin complex, at least composed of KDM5A, GATAD1 and EMSY. Subcellular Location: Nuclear Tissue Specificity: Ubiquitously expressed among various tissue types. Expressed in left ventricular myocytes. DISEASE: Defects in GATAD1 are the cause of cardiomyopathy, dilated type 2B (CMD2B) [MIM:614672]. CMD2B is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. Similarity: Contains 1 GATA-type zinc finger. SWISS: Q8WUU5 Gene ID: 57798 Database links: Entrez Gene: 57798 Human Entrez Gene: 67210 Mouse SwissProt: Q8N5Y5 Human SwissProt: Q8WUU5 Human SwissProt: Q3TS14 Mouse SwissProt: Q8VCQ2 Mouse SwissProt: Q920S3 Mouse SwissProt: Q9CSG2 Mouse Unigene: 21145 Human |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
