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Rabbit Anti-ALS2CR3  antibody (bs-11650R)  
~~~促销代码KT202411~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-11650R
英文名称 Rabbit Anti-ALS2CR3  antibody
中文名称 肌萎缩侧索硬化症相关蛋白3抗体
别    名 ALS2CR3; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;TRAK2_HUMAN; Trafficking kinesin-binding protein 2.  
研究领域 细胞生物  神经生物学  Alzheimer's  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse (predicted: Human,Rat,Pig,Sheep,Cow,Dog)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 101kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ALS2CR3: 701-800/914 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.

Function:
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR

Subunit:
Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.

Subcellular Location:
Cytoplasm (By similarity). Early endosome (By similarity). Mitochondrion (By similarity). Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner

Tissue Specificity:
Widely expressed, with highest expression in heart.

Post-translational modifications:
O-glycosylated

Similarity:
Contains 1 HAP1 N-terminal domain.

SWISS:
O60296

Gene ID:
66008

Database links:

Entrez Gene: 66008 Human

Entrez Gene: 70827 Mouse

Omim: 607334 Human

SwissProt: O60296 Human

Unigene: 152774 Human

Unigene: 222887 Mouse



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