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Rabbit Anti-ZDHHC-18  antibody (bs-8641R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-8641R
英文名称 ZDHHC-18
中文名称 锌指蛋白Zdhhc18抗体
别    名 DHHC-18; DKFZp667O2416; Palmitoyltransferase ZDHHC18; ZDH18_HUMAN; Zdhhc18; Zinc finger DHHC domain-containing protein 18.  
研究领域 细胞生物  免疫学  信号转导  转录调节因子  锌指蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse (predicted: Human,Rat,Chicken,Dog,Pig,Cow,Horse)
产品应用 WB=1:500-2000, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 42kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZDHHC-18: 265-360/388 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.

Function:
Has palmitoyltransferase activity towards HRAS and LCK.

Subcellular Location:
Membrane; Multi-pass membrane protein

Similarity:
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
Contains 1 DHHC-type zinc finger.

SWISS:
Q9NUE0

Gene ID:
84243

Database links:

Entrez Gene: 84243 Human

Entrez Gene: 503610 Mouse

Entrez Gene: 362613 Rat

SwissProt: Q9NUE0 Human

SwissProt: Q5Y5T2 Mouse

SwissProt: Q2TGJ1 Rat

Unigene: 523710 Human

Unigene: 331948 Mouse

Unigene: 203345 Rat



产品图片
Sample:
Lung (Mouse) Lysate at 40 ug
Primary: Anti- ZDHHC-18 (bs-8641R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
Sample:
Lymph node (Mouse) Lysate at 40 ug
Primary: Anti- ZDHHC-18 (bs-8641R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
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