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SORCS3 Rabbit pAb (bs-11503R)  
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产品编号 bs-11503R
英文名称 SORCS3 Rabbit pAb
中文名称 液泡蛋白分选受体SORCS3抗体
别    名 6330404A12Rik; KIAA1059; RP11 107L7.1; SORC3_HUMAN; SORCS 3; SORCS; SORCS3; Sortilin related VPS10 domain containing receptor 3; VPS10 domain containing receptor SorCS3; VPS10 domain receptor protein SORCS 3; VPS10 domain-containing receptor SorCS3.  
研究领域 细胞生物  神经生物学  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat (predicted: Human,Mouse,Pig,Sheep,Cow,Chicken,Dog)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 132 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SORCS3: 201-300/1222 
亚    型
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in brain.

Similarity:
Belongs to the VPS10-related sortilin family. SORCS subfamily.
Contains 6 BNR repeats.
Contains 1 PKD domain.

Gene ID:
22986

Database links:
UniProtKB/Swiss-Prot: Q9UPU3.2

产品图片
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Anti
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