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Adrenodoxin Rabbit pAb (bs-11426R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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产品编号 bs-11426R
英文名称 Adrenodoxin Rabbit pAb
中文名称 肾上腺皮质线粒体铁氧还蛋白抗体
别    名 Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial.  
Specific References  (1)     |     bs-11426R has been referenced in 1 publications.
[IF=8.786] Jiateng Hu. et al. Identification of core cuprotosis-correlated biomarkers in abdominal aortic aneurysm immune microenvironment based on bioinformatics. FRONT IMMUNOL. 2023; 14: 1138126  IF ;  Mouse.  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  生长因子和激素  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat (predicted: Human,Mouse,Sheep)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 13.5 kDa
检测分子量
细胞定位 细胞浆 线粒体
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Adrenodoxin/FDX: 51-150/184 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]

Function:
Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).

Similarity:
Belongs to the adrenodoxin/putidaredoxin family.
Contains 1 2Fe-2S ferredoxin-type domain.

SWISS:
P10109

Gene ID:
2230

Database links:

Entrez Gene: 2230 Human

Entrez Gene: 14148 Mouse

Entrez Gene: 29189 Rat

Omim: 103260 Human

SwissProt: P10109 Human

SwissProt: P46656 Mouse

SwissProt: P24483 Rat

Unigene: 744 Human

Unigene: 1061 Mouse

Unigene: 440190 Mouse

Unigene: 6946 Rat



产品图片
Paraformaldehyde-fixed, paraffin embedded (rat adrenal gland tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C
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