| 产品编号 | bs-11413R |
| 英文名称 | TSKS Rabbit pAb |
| 中文名称 | 睾丸特异激酶底物蛋白抗体 |
| 别 名 | STK22 substrate 1; Stk22s1; Testis specific kinase substrate; Testis specific serine kinase substrate; TSKS; TSKS1; MGC134104; TSKS_HUMAN. |
| 研究领域 | 肿瘤 细胞生物 发育生物学 神经生物学 信号转导 干细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog) |
| 产品应用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 65 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TSKS: 121-170/592 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
TSKS is a 592 amino acid protein that is highly expressed in human testicular tissue. Low levels of TSKS are detectable in prostate, placenta, fetal liver, thymus, and mammary gland tissues. TSKS is found to be downregulated in cancerous testicular tissue from seminoma, teratocarcinoma, embryonal and Leydig cell tumors concurrently with high expression in neighboring premalignant carcinoma. TSKS protein contains an N-terminal signal peptide, but does not contain a transmembrane region. TSKS has many potential phosphorylation and glycosylation sites and is phosphorylated by soluble recombinant TSSK2 in vitro. It is thought that TSKS likely plays a physiological role in spermatogenesis or spermiogenesis. Function: A novel putative serine/threonine kinase substrate gene (TSKS, for testis-specific kinase substrate) is likely the human homolog of the mouse testis-specific serine kinase substrate gene. TSKS exhibits high levels of expression exclusively in human testicular tissue. The expression of TSKS is downregulated in cancerous testicular tissue, in comparison to adjacent normal tissue. These observations suggest a role of TSKS in testicular physiology, most probably in the process of spermatogenesis or spermiogenesis. Subcellular Location: Cytoplasmic Tissue Specificity: Highly expressed in testis. Expressed at low levels in prostate, female breast, placenta, ovary and thymus. Post-translational modifications: Phosphorylated on serine residue(s) by STK22A/TSSK1 and STK22B/TSSK2. SWISS: Q9UJT2 Gene ID: 60385 Database links: Entrez Gene: 60385 Human Omim: 608253 Human SwissProt: Q9UJT2 Human Unigene: 515858 Human |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
