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Rabbit Anti-PTGFR  antibody (bs-11411R)  
~~~促销代码KT202411~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-11411R
英文名称 Rabbit Anti-PTGFR  antibody
中文名称 前列腺素F2a受体抗体PGF2αR
别    名 Prostaglandin F2 alpha Receptor PF2R_HUMAN; PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; Prostaglandin F receptor; Prostaglandin F2-alpha receptor; Prostaglandin receptor 2 alpha; Prostanoid FP receptor; PTGFR; FP; MGC120498; MGC46203.  
研究领域 细胞生物  神经生物学  信号转导  细胞膜受体  G蛋白偶联受体  G蛋白信号  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,Mouse (predicted: Rat,Rabbit,Dog,Horse)
产品应用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 40kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PTGFR: 1-50/359 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P43088

Gene ID:
5737

Database links:

Entrez Gene: 5737 Human

Omim: 600563 Human

SwissProt: P43088 Human

Unigene: 654365 Human



产品图片
Sample: MCF-7(Human) Cell Lysate at 30 ug NIH/3T3(Mouse) Cell Lysate at 30 ug HepG2(Human) Cell Lysate at 30 ug Primary: Anti-PTGFR (bs-11411R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kD Observed band size: 55 kD
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