| 产品编号 | bs-11137R |
| 英文名称 | IL-28R Rabbit pAb |
| 中文名称 | 白细胞介素28受体抗体 |
| 别 名 | Alternative namesIFNLR; Class II cytokine receptor CRF2/12; CRF2/12; Cytokine receptor family 2 member 12; IFN lambda R1; IFNLR1; il-28r1; IL28R alpha; Interferon lambda receptor 1; Interferon lambda receptor; Interleukin 28 receptor alpha chain; LICR2; Likely interleukin or cytokine receptor 2.I28RA_HUMAN |
| 研究领域 | 肿瘤 细胞生物 免疫学 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Dog) |
| 产品应用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 55 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL-28R: 51-150/520 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
IL-28R is a 535 amino acid protein encoded by the human gene IL28RA. IL-28R belongs to the type II cytokine receptor family and contains 1 fibronectin type-III domain. It is a single-pass type I membrane protein found as a heterodimer with IL-10RB. This is a receptor for a small family of structurally-related cytokines that, like IFNs, are known to induce antiviral activity. The expression of IFN-I (IL-28) mRNA is inducible by viral infection in several cell lines. The receptor complex (IL-28R) that is utilized by all three IFN-l proteins for signaling is composed of two subunits, a receptor designated IL-28R and IL-10R2. Both receptor chains are constitutively expressed on a wide variety of human cell lines and tissues and signal through the Jak-STAT (Janus kinases-signal transducers and activators of transcription) pathway. Function: IL28RA is a class II cytokine receptor that interacts with IL10RB to bind IL28A, IL28B, and IL29, which are related to type I interferons. These ligands play a critical role in response to microbial challenge and activate the JAK/STAT signaling system. It heterodimers with IL10RB. There are 4 isoforms as result of alternative splicing. It is widely expressed. IL28RA belongs to the type II cytokine receptor family, and contains 1 fibronectin type III domain. Subunit: Heterodimer with IL10RB. Subcellular Location: Membrane; Single-pass type I membrane protein Tissue Specificity: Widely expressed. Similarity: Belongs to the type II cytokine receptor family. Contains 1 fibronectin type-III domain. SWISS: Q8IU57 Gene ID: 163702 |
| 产品图片 |
Tissue/cell: human laryngeal tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal g
Tissue/cell: Human laryngeal tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal g
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
